5 edition of The Neurobiology of Cocaine found in the catalog.
July 17, 1995
Written in English
|The Physical Object|
|Number of Pages||270|
A study in rats has found that stimulating a key part of the brain reduces compulsive cocaine-seeking and suggests the possibility of changing addictive behavior generally. The study, published in Nature, was conducted by scientists at the Intramural Research Program of the National Institute on Drug Abuse (NIDA), part of the National. Cocaine Interactions with the Endogenous Opioid System / Ellen M. Unterwald --Ch. Neurochemistry of Cocaine Withdrawal / Friedbert Weiss, Loren H. Parsons and Athina Markou --Ch. Chronic Cocaine Action on the Dopamine Transporter / Nancy R. Zahniser, Greg A. Gerhardt and Wayne A. Cass .
Request PDF | The Neurobiology of Cocaine Addiction | Cocaine produces its psychoactive and addictive effects primarily by acting on the brain's limbic system, a set of interconnected regions that. The focus of the book is on the brain processes underlying addiction, in terms of neural systems, neurochemical basis, and molecular changes. Several types of addiction are discussed ranging from illicit drugs - cocaine, amphetamine, and heroin to legal drugs - alcohol and nicotine.5/5(1). The role of dopamine in addiction. Addictive drugs are inherently rewarding. They highjack the brain's dopamine system to increase dopamine levels in the nucleus accumbens, a key focal point for reward neurocircuitry in the brain.6 While dopamine is critical for the rewarding effects of drugs, its role in substance use disorders is still evolving.. Nearly 20 years ago, Nora Volkow (National Cited by:
Much effort has been focused on the development of pharmacotherapies for cocaine use disorder, yet there are no FDA-approved medications. Cocaine exerts its powerful reinforcing effects by acting on mesocorticolimibic circuitry that is primarily associated with dopamine neurotransmission. Accumulating evidence continues to implicate the noradrenergic system as key to cocaine’s effects. Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain. The premier text on substance abuse and addictive behaviors is now in its updated and expanded Fourth Edition, with up-to-the-minute insights from more than experts at the front lines of patient management and research. This edition features expanded coverage of the neurobiology of abused substances, new pharmacologic therapies for addictions, and complete information on “club drugs 4/5(3).
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SyntaxTextGen not activatedwith the type of drug used. For example, with stimulants such as cocaine, pdf “high” is followed by feelings of power, self-confidence, and increased energy. In contrast, the euphoria caused by opiates such as heroin is followed by feelings of relaxation and satisfaction.
z To feel better.The consummatory component represents the actual “consuming” of the goal (e.g., cocaine reaches the brain). An important question in the neurobiology of cocaine concerns the role of dopamine: If cocaine increases brain dopamine when consumed, does dopamine only play a role during the consummatory phase of cocaine use?Cocaine and the Brain: Ebook Neurobiology of Addiction In the eyes ebook the public, the word addict stirs up a negative image: a person of low moral character who willfully chooses to engage in questionable behavior.
This image is perpetuated in the media; on a recent episode of E.R., the chief surgeon.